Phorbol 12-Myristate 13-Acetate (PMA) 98% (CAS:16561-29-8) is an ultra-pure, crystalline PKC activator derived from Croton tiglium seeds, validated for tumor promotion and immunology research. With ≥98% HPLC-verified purity, it reliably induces PKC-dependent pathways at 1-100 nM concentrations in models ranging from DMBA-initiated carcinogenesis to neutrophil NETosis studies.