福彩快三在哪里买,滚球体育app下载更新,米乐app官网,开心彩票登录,kok手机网页版登录,欧亚国际网站,爱博体育官网入口网页版

83207-58-3

  • Product Name:Astragaloside A
  • Molecular Formula:C41H68O14
  • Molecular Weight:784.983
  • Appearance:white powder
Inquiry

Product Details

pd_meltingpoint:284-286oC

Appearance:white powder

Purity:99%

Trustworthy Factory Supply Astragaloside A, Factory Sells 83207-58-3 with Lowest Price

  • Molecular Formula:C41H68O14
  • Molecular Weight:784.983
  • Appearance/Colour:white powder 
  • Vapor Pressure:0mmHg at 25°C 
  • Melting Point:284-286oC 
  • Refractive Index:1.62 
  • Boiling Point:895.666 °C at 760 mmHg 
  • PKA:12.91±0.70(Predicted) 
  • Flash Point:495.481 °C 
  • PSA:228.22000 
  • Density:1.395 g/cm3 
  • LogP:0.72410 

Astragaloside A(Cas 83207-58-3) Usage

Description

Astragaloside A (Astragaloside IV) is the primary pure saponin isolated from Astragalus membranaceus, which has been widely used for the treatment of cardiovascular diseases.

Uses

Astragalosides are bioactive saponins isolated from dried roots of plants of the genus Astragalus, which is used in traditional Chinese medicine. Astragaloside A, also known as astragaloside IV, is known to have diverse protective effects for the cardiovascular, immune, digestive, and nervous systems. More specifically, it protects cardiomyocytes from apoptosis resulting from ischemia/reperfusion and inhibits inflammation signaled through TNF-α. Furthermore, astragaloside A stimulates angiogenesis, promotes the differentiation of neural stem cells, and increases neuroregeneration.

Health effects

As the main active ingredient of the Chinese medicine Astragalus membranaceus, Astragaloside A has a good regulatory effect on the heart. It can protect against ischemic and hypoxic cardiomyocytes, protect the heart structure, and enhance heart function.

Pharmaceutical Applications

Astrageloside A has multiple pharmacologic effects, including anti-inflammatory, antifibrotic, antioxidative stress, anti-asthma, antidiabetes, immunoregulation, and cardioprotective effect via numerous signaling pathways. According to the existing studies and clinical practices, Astragaloside A possesses potential for broad application in many diseases.

InChI:InChI=1/C41H68O14/c1-35(2)24(54-33-29(48)26(45)20(44)17-51-33)9-11-41-18-40(41)13-12-37(5)31(39(7)10-8-25(55-39)36(3,4)50)19(43)15-38(37,6)23(40)14-21(32(35)41)52-34-30(49)28(47)27(46)22(16-42)53-34/h19-34,42-50H,8-18H2,1-7H3/t19-,20+,21-,22+,23-,24-,25-,26-,27?,28-,29+,30?,31-,32-,33-,34+,37+,38-,39+,40-,41+/m0/s1

83207-58-3 Relevant articles

TRITERPENE GLYCOSIDES OF Astragalus AND THEIR GENINS. XV. CYCLOSIVERSIOSIDES B AND D FROM Astragalus basineri

Umarova, R. U.,Svechnikova, A. N.,Abdullaev, N. D.,Gorovich, M. B.,Abubakirov, N. K.

, p. 174 - 177 (1984)

Two new glycosides have been isolated fr...

Functional Characterization and Protein Engineering of a Triterpene 3-/6-/2′-O-Glycosyltransferase Reveal a Conserved Residue Critical for the Regiospecificity

Bao, Yang-Oujie,Gao, Bai-Han,Li, Fu-Dong,Qiao, Xue,Shi, Xiao-Meng,Su, Hui-Fei,Wang, Hai-Dong,Ye, Min,Yi, Yang,Zhang, Meng

supporting information, (2022/01/06)

Engineering the function of triterpene g...

Synthetic Access Toward Cycloastragenol Glycosides

Liu, Ting,Liao, Jin-Xi,Hu, Yang,Tu, Yuan-Hong,Sun, Jian-Song

, p. 4170 - 4178 (2017/04/27)

The first efficient synthetic approach t...

Triterpene glycosides from Tragacantha stipulosa and their genins. Structure of cyclostipuloside E

Kaipnazarov,Uteniyazov,Saatov

, p. 40 - 44 (2007/10/03)

The known compound trojanoside A(1) and ...

83207-58-3 Process route

3-O-(2,3,4-tri-O-benzoyl-β-D-xylopyranosyl)-6-O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-16,25-di-O-acetylcycloastragenol

3-O-(2,3,4-tri-O-benzoyl-β-D-xylopyranosyl)-6-O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-16,25-di-O-acetylcycloastragenol

astragaloside IV
83207-58-3,84687-43-4

astragaloside IV

Conditions
Conditions Yield
With sodium methylate; In methanol; at 20 ℃; for 15h;
76%
astragaloside VI
84687-45-6

astragaloside VI

astragaloside IV
83207-58-3,84687-43-4

astragaloside IV

Conditions
Conditions Yield
hesperidinase; In water; acetone; at 35 ℃; for 36h;
35 mg

83207-58-3 Upstream products

  • 88192-83-0
    88192-83-0

    cyclosiversioside H

  • 86764-11-6
    86764-11-6

    isoastragalosides II

  • 84676-88-0
    84676-88-0

    isoastragaloside I

  • 84687-46-7
    84687-46-7

    (3β,6α,16β,20R,24S)-20,24-epoxy-16-hydroxy-3-(β-D-xylopyranosyloxy)-9,19-cyclolanostane-6,25-diyl bis[β-D-glucopyranoside]

83207-58-3 Downstream products

  • 84605-18-5
    84605-18-5

    cycloastragenol

  • 86764-12-7
    86764-12-7

    cyclosieversigenin 6-O-β-D-glucopyranoside

  • 86541-79-9
    86541-79-9

    astragenol

  • 86541-83-5
    86541-83-5

    cyclosieversigenin 3-O-β-D-xylopyranoside

Relevant Products

苗栗县| 庆元县| 林周县| 油尖旺区| 正安县| 革吉县| 贺兰县| 庆城县| 淮北市| 乌兰浩特市| 齐齐哈尔市| 广州市| 东乡县| 峡江县| 河源市| 宝鸡市| 绍兴市| 炎陵县| 霍城县| 绵竹市| 赤城县| 乌鲁木齐市| 齐河县| 邯郸市| 牟定县| 周口市| 北川| 惠州市| 南岸区| 七台河市| 阿图什市| 高平市| 惠州市| 云安县| 尼勒克县| 化州市| 安泽县| 肃南| 余姚市| 措美县| 康平县|